Definition

An antibody-drug conjugate (ADC) composed of a monoclonal antibody directed against an as of yet undisclosed tumor-associated antigen (TAA) linked to an undisclosed cytotoxic agent, with potential antineoplastic activity. Upon intravenous administration of ADC AMT-116, the monoclonal antibody moiety targets and binds to the TAA expressed on tumor cells. Upon binding and internalization, the cytotoxic agent is released and kills tumor cells expressing this particular TAA through an as of yet undisclosed mechanism.