Single Biggest Cancer Dictionary in the World

What is

monoclonal antibody CEP-37250/KHK2804

?

Pronunciation: /ˌmɑnəˈkloʊnəl ˈæntɪˌbɑdi sɛp thirty-seven* ˈθaʊzənd, tu ˈhənərd ənd ˈfɪfti khk* tu ˈθaʊzənd, eɪt ˈhənərd ənd fɔr/

monoclonal antibody CEP-37250/KHK2804

Definition

A humanized monoclonal antibody targeting glycolipids, with potential immunomodulating and antineoplastic activity. Upon administration, monoclonal antibody CEP-37250/KHK2804 targets and binds to a specific tumor antigen, thereby stimulating the immune system to exert an antibody-dependent cellular cytotoxicity (ADCC) against the tumor associated antigen (TAA)-expressing cancer cells. This agent has shown to be active in both wild-type and mutant K-RAS-expressing colorectal cancer cells.