Definition

A rare condition marked by headaches, vision problems, mental changes, seizures, and swelling in the brain. The symptoms of RPLS usually come on quickly and can be serious and life threatening. When treated, symptoms often go away within days or weeks. RPLS may occur in patients with certain conditions, such as high blood pressure, eclampsia, severe infection, kidney disease, and certain autoimmune diseases. It may also occur in patients treated with certain anticancer drugs and immunosuppressive drugs. Also called posterior reversible encephalopathy syndrome, PRES, and reversible posterior leukoencephalopathy syndrome.