Definition

An area of abnormal cells that forms on the surface of certain organs, such as the cervix, vagina, vulva, anus, and esophagus. LSILs look slightly abnormal when looked at under a microscope. They are usually caused by infection with certain types of human papillomavirus (HPV) and are found when a Pap test or biopsy is done. LSILs usually go away on their own without treatment, but sometimes they can become cancer and spread into nearby tissue. LSIL is sometimes called mild dysplasia. Also called low-grade squamous intraepithelial lesion.