Definition

The large network consisting of protein fibers and other molecules that gives shape and structure to cells in the body. The intracellular matrix helps organize structures within the cell called organelles and other substances found in the fluid inside the cell. It plays an important role in many cell functions, including cell movement, signaling, and division. Abnormal changes in the intracellular matrix may lead to the development of many different diseases, including cancer. The intracellular matrix can also affect how cancer cells grow and spread in the body. Also called cytoskeleton.