Definition

An abbreviation for a chemotherapy combination used to treat certain types of non-Hodgkin lymphoma. It includes the drugs etoposide phosphate, prednisone, vincristine sulfate (Oncovin), cyclophosphamide, doxorubicin hydrochloride (hydroxydaunorubicin), and rituximab. During each treatment cycle, the doses of some of the drugs may be increased or decreased to allow the patient to receive the dose that works the best with the fewest side effects. Also called DA-EPOCH-R, dose-adjusted EPOCH-R, and dose-adjusted EPOCH-R regimen.