Definition

A type of clinical trial that tests how well a new drug or other substance works in patients who have different types of cancer that all have the same mutation or biomarker. In bucket trials, patients all receive the same treatment that targets the specific mutation or biomarker found in their cancer. Bucket trials may allow new drugs to be tested and approved more quickly than traditional clinical trials. Bucket trials may also be useful for studying rare cancers and cancers with rare genetic changes. Also called basket trial.