Single Biggest Cancer Dictionary in the World
What is BRAF (V600E) kinase inhibitor RO5185426?
Pronunciation: /braf* vi sɪks ˈhənərd i kinase* ˌɪnˈhɪbətər roʊ faɪv ˈmɪljən, wən ˈhənərd ənd eighty-five* ˈθaʊzənd, fɔr ˈhənərd ənd twenty-six*/
BRAF (V600E) kinase inhibitor RO5185426
Definition
A drug used to treat Erdheim-Chester disease (a very rare type of histiocytosis) and advanced melanoma that have a certain mutation (change) in the BRAF gene. It is also being studied in the treatment of other types of cancer. BRAF (V600E) kinase inhibitor RO5185426 blocks certain proteins made by the mutated BRAF gene, which may help keep cancer cells from growing. It is a type of kinase inhibitor. Also called PLX4032, RG7204, vemurafenib, and Zelboraf.