Single Biggest Cancer Dictionary in the World
What is ONYX-015?
Pronunciation: /ˈɑnɪks ˈfɪfˈtin/
ONYX-015
Definition
An E1B-55kDa-deleted adenovirus that is able to selectively replicate in and lyse TP53-deficient human tumor cells. After tumor cell lysis, released viruses infect neighboring tumor cells, tripping a chain of ONYX-015-mediated tumor cell cytotoxicity.