Single Biggest Cancer Dictionary in the World

What is

human papillomavirus 16 E7 peptide

?

Pronunciation: /ˈjumən papillomavirus* ˈsɪkˈstin i ˈsɛvən ˈpɛpˌtaɪd/

human papillomavirus 16 E7 peptide

Definition

A synthetic peptide sequence of human papillomavirus (HPV) E7 nuclear protein which is used to produce vaccines against HPV infection and HPV-related neoplasms. HPV E7 oncogenic protein binds the retinoblastoma tumor suppressor protein, pRB, as well as a number of other cellular proteins, and serves as a transcriptional activator. This protein is important in the induction and maintenance of cellular transformation and is co-expressed in the majority of HPV-containing carcinomas.