Single Biggest Cancer Dictionary in the World

What is fluorine F 18-BMS-986229?

Pronunciation: /ˈflʊˌrin ɛf ˈeɪˈtin bms* naɪn ˈhənərd ənd eighty-six* ˈθaʊzənd, tu ˈhənərd ənd twenty-nine*/

fluorine F 18-BMS-986229

Definition

A radiotracer composed of BMS-986229, a tracer targeting programmed cell death-1 ligand 1 (PD-L1; cluster of differentiation 274; CD274), labeled with the radioisotope fluorine F 18, with potential use for assessing PD-L1 tumor antigen expression using positron emission tomography (PET). Upon administration of fluorine F 18-BMS-986229, the BMS-986229 moiety targets and binds to PD-L1 expressed on certain tumor cells. Upon PET imaging, the radiotracer can be visualized and the extent of PD-L1 expression can be assessed.