Single Biggest Cancer Dictionary in the World

What is antibody drug conjugate TORL-1-23?

Pronunciation: /ˈæntɪˌbɑdi drəg ˌkɑnʤəˈgeɪt torl* wən tˈwɛntiθˌri/

antibody drug conjugate TORL-1-23

Definition

An antibody-drug conjugate (ADC) composed of a monoclonal antibody against an unnamed tumor-associated antigen (TAA) linked to an as of yet undisclosed cytotoxic agent, with potential antineoplastic activity. Upon intravenous administration, the monoclonal antibody moiety of TORL-1-23 targets and binds to the TAA expressed on tumor cells. Upon binding and internalization, the cytotoxic agent is released and kills the TAA-expressing cancer cells, through an as of yet unknown mechanism of action.