Single Biggest Cancer Dictionary in the World

What is antibody-drug conjugate SC-004?

Pronunciation: /ˈæntɪˌbɑdi drəg ˌkɑnʤəˈgeɪt sc* fɔr/

antibody-drug conjugate SC-004

Definition

An antibody-drug conjugate (ADC) composed of a proprietary monoclonal antibody against a tumor-associated antigen (TAA) linked to a currently undisclosed cytotoxic agent, with potential antineoplastic activity. Upon intravenous administration, the monoclonal antibody moiety of SC-004 targets and binds to the TAA expressed on tumor cells. Upon binding and internalization, the cytotoxic agent is released and kills the TAA-expressing cancer cells, through an unknown mechanism of action.