Single Biggest Cancer Dictionary in the World
What is adenoviral cancer vaccine PF-06936308?
Pronunciation: /adenoviral* ˈkænsər ˌvækˈsin pf* sɪks ˈmɪljən, naɪn ˈhənərd ənd thirty-six* ˈθaʊzənd, θri ˈhənərd ənd eɪt/
adenoviral cancer vaccine PF-06936308
Definition
A cancer vaccine composed of a replication-defective E1-deleted adenovirus vector based on chimpanzee adenovirus serotype 68 (AdC68) expressing three not yet disclosed tumor-associated antigens (TAAs), with potential immunostimulating and antineoplastic activities. Upon vaccination with the adenoviral cancer vaccine PF-06936308, the adenovirus infects cells and expresses the TAAs. In turn, the TAAs activate the immune system to produce a cytotoxic T-lymphocyte (CTL) response against cells expressing the TAAs.