Single Biggest Cancer Dictionary in the World
What is
5-fluorouracil/salicylic acid topical solution
?Pronunciation: /faɪv fluorouracil* salicylic* ˈæsəd ˈtɑpɪkəl səˈluʃən/
5-fluorouracil/salicylic acid topical solution
Definition
A topical formulation containing 0.5 % of antimetabolite 5-fluorouracil (5-FU) and 10% of salicylic acid, with potential antimitotic and keratolytic activity. Upon cutaneous application, 5-FU in the 5-fluorouracil/salicylic acid topical solution impedes pyrimidine metabolism thereby inhibiting cell growth, while the salicylic acid induces anti-inflammatory response and results in keratolytic effect. This may result in the breakdown of keratinocytes and prevent proliferation of keratinocytes locally.