Definition

A drug used to treat adults with certain types of prostate cancer or ovarian epithelial, fallopian tube, or primary peritoneal cancer. It is also being studied in the treatment of other types of cancer. PARP-1 inhibitor AG014699 blocks an enzyme involved in many cell functions, including the repair of DNA damage. Blocking this enzyme may help keep cancer cells from repairing their damaged DNA, causing them to die. PARP-1 inhibitor AG014699 is a type of PARP inhibitor. Also called AG014699, Rubraca, and rucaparib camsylate.