Definition

An abbreviation for a chemotherapy combination used to treat Ewing sarcoma and other sarcomas, such as mesenchymal chondrosarcoma. It includes the drugs vincristine sulfate, doxorubicin hydrochloride (Adriamycin), and cyclophosphamide, followed by ifosfamide and etoposide phosphate. Also called VAC-IE, VAC-IE regimen, and VAdriaC-IE regimen.