Single Biggest Cancer Dictionary in the World

What is

tumor mutational burden

?

Pronunciation: /ˈtumər mutational* ˈbərdən/

tumor mutational burden

Definition

The total number of mutations (changes) found in the DNA of cancer cells. Knowing the tumor mutational burden may help plan the best treatment. For example, tumors that have a high number of mutations appear to be more likely to respond to certain types of immunotherapy. Tumor mutational burden is being used as a type of biomarker. Also called TMB.