Definition

A drug used alone or with other drugs to treat adults with certain types of diffuse large B-cell lymphoma or multiple myeloma. It is used in patients whose cancer has already been treated with other anticancer therapy. It is also being studied in the treatment of other types of cancer. Selinexor blocks a protein called CRM1, which may help keep cancer cells from growing and may kill them. It is a type of small molecule inhibitor. Also called Xpovio.