Definition

A drug used to treat adults with intermediate-risk or high-risk myelofibrosis (MF), including primary MF, post-polycythemia vera MF, and post-essential thrombocythemia MF. It is used in patients who have a very low blood platelet count. It is also being studied in the treatment of other conditions and some types of cancer. Pacritinib citrate blocks JAK2 and other proteins, which may help keep abnormal blood cells or cancer cells from growing. It is a type of kinase inhibitor. Also called Vonjo.