Definition

A substance being studied in the treatment of myelodysplastic syndromes and some types of leukemia. It binds to CD33, a protein on the surface of certain normal blood stem cells and some abnormal blood cells. It causes the immune system to kill these cells. MoAb HuM195 is a type of monoclonal antibody. Also called lintuzumab and monoclonal antibody HuM195.