Definition

A drug used with other drugs to treat adults with HER2-positive breast cancer that has spread to other parts of the body. It is used in patients who have already received at least two anti-HER2 treatments, including at least one for metastatic disease. It is also being studied in the treatment of other types of cancer. Margenza binds to a protein called HER2, which is found on some cancer cells. This may help the immune system kill cancer cells. Margenza is a type of monoclonal antibody. Also called margetuximab.