Definition

A drug used to treat anemia in adults with certain types of myelodysplastic syndromes or myelodysplastic/myeloproliferative neoplasms who need regular red blood cell transfusions and whose anemia did not respond to or cannot be treated with an erythropoiesis-stimulating agent. Luspatercept is also used to treat anemia in adults with beta thalassemia (an inherited blood disorder) who need regular red blood cell transfusions. It is also being studied in the treatment of other conditions. Luspatercept helps the bone marrow make more red blood cells. It is a type of antianemic and a type of recombinant fusion protein. Also called Reblozyl.