Definition

A protein involved in normal cell growth. Human EGF receptor 2 may be made in larger than normal amounts by some types of cancer cells, including breast, ovarian, bladder, pancreatic, stomach, and esophageal cancers. This may cause cancer cells to grow more quickly and spread to other parts of the body. Checking the amount of human EGF receptor 2 on some types of cancer cells may help plan treatment. Also called c-erbB-2, HER2, HER2/neu, and human epidermal growth factor receptor 2.