Definition

A drug used to prevent nausea and vomiting caused by chemotherapy and radiation therapy and to prevent and treat nausea and vomiting after surgery in adults. Granisetron hydrochloride blocks the action of a chemical called serotonin, which binds to certain nerves and may trigger nausea and vomiting. Blocking serotonin may help lessen nausea and vomiting. Granisetron hydrochloride is a type of antiemetic and a type of serotonin receptor antagonist.