Definition

A drug used with surgery and radiation therapy to treat high-grade glioma that has not already been treated and with surgery to treat glioblastoma multiforme that has recurred (come back). Gliadel Wafer is a form of carmustine contained in a wafer. The wafer has a coating that dissolves slowly and releases carmustine directly into the area where the brain tumor was removed. This form may have fewer side effects and work better than other forms of carmustine. Gliadel Wafer is a type of alkylating agent and a type of nitrosourea. Also called carmustine implant and polifeprosan 20 carmustine implant.