Definition

A gene that makes a protein involved in cell division, cell growth and maturation, formation of new blood vessels, wound healing, and the growth and development of many parts of the body. Mutations (changes) in the FGFR1 gene may cause the FGFR1 protein to become overactive, which may cause cells to grow and divide too quickly or in an uncontrolled way. FGFR1 gene mutations have been found in certain genetic conditions and in some types of cancer. Also called fibroblast growth factor receptor 1 gene.