Definition

A drug used to treat adults with certain types of HER2-positive or HER2-low breast cancer, HER2-positive stomach cancer, gastroesophageal junction cancer, or other solid tumor, or non-small cell lung cancer that has a certain mutation in the HER2 gene. It is also being studied in the treatment of other types of cancer. Fam-trastuzumab deruxtecan contains a monoclonal antibody called trastuzumab that binds to a protein called HER2, which is found on some cancer cells. It also contains an anticancer drug called deruxtecan, which may help kill cancer cells. Fam-trastuzumab deruxtecan is a type of antibody-drug conjugate. Also called Enhertu and trastuzumab deruxtecan.