Single Biggest Cancer Dictionary in the World

What is estrogen receptor negative?

Pronunciation: /ˈɛstrəʤən riˈsɛptər ˈnɛgətɪv/

estrogen receptor negative

Definition

Describes cells that do not have a protein that binds to the hormone estrogen. Cancer cells that are estrogen receptor negative do not need estrogen to grow. This means that they will keep growing when estrogen is not present and do not stop growing when treated with substances that block estrogen from binding. Also called ER negative.