Definition

A drug used to treat severe side effects caused by certain types of anticancer drugs. It is used under the brand names Totect and Zinecard to reduce heart damage in women who are receiving doxorubicin for breast cancer that has spread to other parts of the body. It is also used under the brand name Totect to treat the toxic effects of an anticancer drug that leaks from a vein into surrounding tissue and causes tissue damage. Dexrazoxane hydrochloride is also being studied in the treatment of some types of cancer. It is a type of cardioprotective agent, a type of chemoprotective agent, and a type of topoisomerase inhibitor. Dexrazoxane is the active ingredient of dexrazoxane hydrochloride.