Definition

A drug used to treat adults with certain types of diffuse large B-cell lymphoma or large B-cell lymphoma that came back or did not get better after treatment with at least two other systemic therapies. It is also being studied in the treatment of other types of cancer. Columvi binds to a protein called CD3, which is found on T cells (a type of white blood cell). It also binds to a protein called CD20, which is found on B cells (another type of white blood cell) and some lymphoma cells. This may help the immune system kill cancer cells. Columvi is a type of bispecific monoclonal antibody. Also called glofitamab.