Definition

A cervical biopsy finding that means severely abnormal cells were found on the surface of the cervix. CIN 3 is usually caused by infection with certain types of human papillomavirus (HPV). CIN 3 is not cancer but may become cancer and spread to nearby normal tissue if not treated. Treatment for CIN 3 may include cryotherapy, laser therapy, loop electrosurgical procedure (LEEP), or cone biopsy to remove or destroy the abnormal tissue. CIN 3 is sometimes called high-grade or severe dysplasia. Also called cervical squamous intraepithelial neoplasia 3.