Definition

A drug used with plasma exchange and immunosuppressive therapy to treat acquired thrombotic thrombocytopenic purpura (aTTP). aTTP is a rare blood disorder in which blood clots form in small blood vessels throughout the body. Caplacizumab binds to a protein called VWF, which may help keep blood clots from forming. It is a type of nanobody (a tiny antibody). Also called Cablivi.