Definition

A rare, fast-growing cancer that affects the blood, bone marrow, and skin. It can also affect the lymph nodes, spleen, and central nervous system. Most patients with BPDCN have red-brown or deep purple skin lesions on one or more areas of the body. BPDCN usually occurs in older adults and is difficult to diagnose and treat. Also called blastic plasmacytoid dendritic cell neoplasm.