Definition

A substance that binds to a protein called CD38, which is found on some types of blood cells and in high levels on some cancer cells, including myeloma cells. Anti-CD38 monoclonal antibody may block the CD38 protein and help the immune system kill cancer cells. Some anti-CD38 monoclonal antibodies are being used to treat multiple myeloma. They are also being studied in the treatment of other types of cancer.