Single Biggest Cancer Dictionary in the World
What is
yttrium Y 90 anti-CD45 monoclonal antibody AHN-12
?Pronunciation: /ˈɪtriəm waɪ ˈnaɪnti ˈænˌti ˈsiˈdi ˈfɔrtiˌfaɪv ˌmɑnəˈkloʊnəl ˈæntɪˌbɑdi æn twɛlv/
yttrium Y 90 anti-CD45 monoclonal antibody AHN-12
Definition
A radioimmunoconjugate comprised of the monoclonal antibody AHN-12 conjugated to the radioisotope yttrium 90 with potential radioimmunotherapeutic activity. Yttrium Y 90 monoclonal antibody AHN-12 binds to the tyrosine phosphatase CD45, expressed on the surface of normal and malignant hematopoietic cells. After binding and internalization by CD45-expressing tumor cells, this agent may deliver a cytotoxic dose of beta radiation.