Single Biggest Cancer Dictionary in the World
What is vascular endothelial growth factor antisense oligonucleotide?
Pronunciation: /ˈvæskjələr ˌɛndoʊˈθiˌliəl groʊθ ˈfæktər ˈæntiˌsɛns oligonucleotide*/
vascular endothelial growth factor antisense oligonucleotide
Definition
An antisense oligonucleotide with potential antiangiogenesis activity. Vascular endothelial growth factor (VEGF) antisense oligonucleotide binds directly to binds VEGF A/C/D mRNA, leading to mRNA degradation and the inhibition of VEGF A-mediated angiogenesis and VEGF C/D-mediated lymphangiogenesis.