Single Biggest Cancer Dictionary in the World
What is umbilical cord blood-derived CD4+/CD25+ T-regulatory cells CK0801?
Pronunciation: /əmˈbɪlɪkəl kɔrd bləd dəraɪvd ˈsiˈdi fɔr ˈsiˈdi tˈwɛntiˌfaɪv ti ˈrɛgjələˌtɔri sɛlz ck* eɪt ˈhənərd ənd wən/
umbilical cord blood-derived CD4+/CD25+ T-regulatory cells CK0801
Definition
A preparation composed of allogeneic umbilical cord blood (UCB)-derived, ex vivo expanded and enhanced CD4+/CD25+ T-regulatory cells (Tregs) with potential immunomodulatory activity. Upon administration, the UCB-derived CD4+/CD25+ Tregs CK0801 may promote immunologic homeostasis and prevent autoimmunity by suppressing self-reactive T cells. This may induce tolerance to allogeneic organ transplants, prevent graft-versus-host disease (GvHD), and suppress autoimmune pathology.