Single Biggest Cancer Dictionary in the World
What is allogeneic cellular vaccine 1650-G?
Pronunciation: /allogeneic* ˈsɛljələr ˌvækˈsin wən ˈθaʊzənd, sɪks ˈhənərd ənd ˈfɪfti ʤi/
allogeneic cellular vaccine 1650-G
Definition
A pluripotent, allogeneic, tumor cell vaccine composed of irradiated tumor cells from the non-small cell lung cancer (NSCLC) cell line 1650 and the immunoadjuvant recombinant granulocyte-macrophage colony stimulating factor (GM-CSF) (1650-G), with potential immunostimulating and antineoplastic activities. Upon administration, allogeneic cellular vaccine 1650-G may stimulate the immune system to exert a cytotoxic T-lymphocyte (CTL) immune response against tumor-associated antigens (TAAs) expressed on NSCLC cells. GM-CSF potentiates the antitumor immune response. The 1650 cell line is used as a source for TAAs.