Single Biggest Cancer Dictionary in the World
What is topoisomerase I inhibitor Genz-644282?
Pronunciation: /topoisomerase* aɪ ˌɪnˈhɪbətər ʤɛnz sɪks ˈhənərd ənd forty-four* ˈθaʊzənd, tu ˈhənərd ənd eighty-two*/
topoisomerase I inhibitor Genz-644282
Definition
A non-camptothecin inhibitor of topoisomerase I with potential antineoplastic activity. Topoisomerase I inhibitor Genz-644282 binds to and inhibits the enzyme topoisomerase I, which may result in the inhibition of repair of single-strand DNA breaks, DNA replication, and tumor cell growth in susceptible tumor cell populations.