Single Biggest Cancer Dictionary in the World
What is telomerase: 540-548 peptide vaccine?
Pronunciation: /təˈloʊmərˌeɪz faɪv ˈhənərd ənd ˈfɔrti faɪv ˈhənərd ənd forty-eight* ˈpɛpˌtaɪd ˌvækˈsin/
telomerase: 540-548 peptide vaccine
Definition
A recombinant peptide consisting of the amino acid residues 540 to 548 of the human telomerase reverse transcriptase (hTERT). Telomerase expression has been directly linked to tumor development; its catalytic subunit is expressed in the majority of human cancer cells, but infrequently in normal cells. Vaccination with telomerase:540-548 peptide may stimulate cytotoxic T cells to recognize and kill telomerase-expressing cells.