Single Biggest Cancer Dictionary in the World
What is T-regulatory cell-enriched donor cells?
Pronunciation: /ti ˈrɛgjələˌtɔri sɛl ɛnˈrɪʧt ˈdoʊnər sɛlz/
T-regulatory cell-enriched donor cells
Definition
A preparation of donor-derived T cells that have been enriched with donor T-regulatory (Treg) cells, with potential immunomodulating activity. Upon administration of the Treg cell-enriched donor cells prior to hematopoietic stem cell transplantation (HSCT), the donor cells may induce tolerance to HSCT and may reduce risk of relapse and graft-versus-host-disease (GVHD) in hematologic malignancies.