Single Biggest Cancer Dictionary in the World

What is

synthetic peptides E-PRA and E-PSM vaccine

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Pronunciation: /sɪnˈθɛtɪk ˈpɛpˌtaɪdz i pra* ənd i psm* ˌvækˈsin/

synthetic peptides E-PRA and E-PSM vaccine

Definition

A cancer vaccine consisting of E-PRA and E-PSM, two synthetic peptide analogs of PRAME (PReferential Antigen MElanoma) and PSMA (Prostate Specific Membrane Antigen), with potential immunostimulating activity. Upon direct administration into lymph nodes, synthetic peptides E-PRA and E-PSM vaccine may stimulate a cytotoxic T-lymphocyte (CTL) response against PRAME- and PSMA-expressing tumor cells. PRAME and PSMA are tumor-associated antigens upregulated and expressed on the cell surfaces of certain tumor cell types.