Single Biggest Cancer Dictionary in the World
What is synthetic glioblastoma tumor-associated peptides vaccine therapy APVAC1?
Pronunciation: /sɪnˈθɛtɪk glioblastoma* ˈtumər əˈsoʊʃiˌeɪtəd ˈpɛpˌtaɪdz ˌvækˈsin ˈθɛrəpi apvac* wən/
synthetic glioblastoma tumor-associated peptides vaccine therapy APVAC1
Definition
A personalized peptide-based cancer vaccine comprised of five to ten peptides associated with glioblastoma (GB), with potential immunomodulating and antineoplastic activities. Vaccination with synthetic GB tumor-associated peptides vaccine therapy APVAC1 stimulates the host immune system to mount a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing the tumor associated peptides, and results in decreased GB growth. The peptides are derived from a glioma actively-personalized vaccine consortium (GAPVAC) warehouse and are specifically selected based on the patient’s expression of tumor-associated antigens.