Single Biggest Cancer Dictionary in the World
What is siRNA-expressing SV40 vector?
Pronunciation: /ˈsərnə ɪkˈsprɛsɪŋ sv* ˈfɔrti ˈvɛktər/
siRNA-expressing SV40 vector
Definition
A simian virus 40 (SV40)-based shuttle vector, encoding small interfering RNA (siRNA), with potential antineoplastic activity. The expression of siRNA in target tumor cells transfected with an siRNA-expressing SV40 vector may result in siRNA-mediated silencing of target oncogenes and, so, the inhibition of tumor cell growth and the induction of tumor cell death.