Definition

The monohydrate form of relebactam, a beta-lactamase inhibitor, that can be used to inhibit the breakdown of certain drugs, such as the broad spectrum beta-lactam carbapenem antibiotic imipenem. Upon administration of relebactam monohydrate, relebactam targets, binds to and inhibits beta-lactamase. This reduces the breakdown of drugs, such as imipenem, and thereby increases the activity and therapeutic effect of such drugs that would otherwise be inactivated by beta-lactamase.