Single Biggest Cancer Dictionary in the World
What is pan-HER kinase inhibitor AC480?
Pronunciation: /pæn hər kinase* ˌɪnˈhɪbətər ˈeɪˈsi fɔr ˈhənərd ənd ˈeɪti/
pan-HER kinase inhibitor AC480
Definition
An orally bioavailable pan-HER tyrosine kinase inhibitor with potential antineoplastic activity. BMS-599626 inhibits human epidermal growth factor receptors (HER) HER1, HER2 and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors.