Single Biggest Cancer Dictionary in the World
What is NM-3?
Pronunciation: /nm* θri/
NM-3
Definition
An orally bioavailable antiangiogenic isocoumarin with potential antineoplastic activity. NM-3 inhibits vascular endothelial growth factor (VEGF), a pro-angiogenic growth factor, thereby inhibiting endothelial cell proliferation. This agent also induces apoptosis by a mechanism involving reactive oxygen species.