Definition

A nanoparticle-based formulation composed of a nanoscale coordination polymer (NCP) complex containing two as of yet undisclosed anti-tumor agents, with potential antineoplastic activities. Upon intravenous administration, nanoparticle formulation CPI-300 delivers the anti-tumor agents to tumor cells, which may lead, through as of yet undisclosed mechanism of actions (MoAs), to specific tumor cell killing and inhibition of proliferation of tumor cells.