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What is mouse gp100 plasmid DNA vaccine?
Pronunciation: /maʊs gp* wən ˈhənərd plasmid* ˈdiˌɛˈneɪ ˌvækˈsin/
mouse gp100 plasmid DNA vaccine
Definition
A vaccine consisting of a plasmid DNA encoding the murine melanoma-associated antigen gp100. Upon administration, expressed gp100 antigen may stimulate a cytotoxic T cell HLA-A2.1-restricted immune response against tumor cells that express the gp100 antigen, resulting in tumor cell lysis.